Senior Director, Commercial Operations

Dompé is an Italian bio-pharmaceutical company that focuses on innovation, where a long tradition in the field of personal wellness goes hand-in-hand with a commitment to research and development to meet unsatisfied therapeutic needs.  

Established in 1940 in Milan, Dompé has an industrial and biotech research hub in L’Aquila, in addition to branches in Europe (Barcelona, Berlin, Paris and Tirana). The company has approximately 900 employees. The US headquarters of Dompé are based in Boston (R&D) and in the San Francisco Bay Area (Commercial Operations).  

Job Summary:

The Senior Director of Commercial Operations is responsible for leading the strategy, design, and execution of core operations functions that enable the U.S. commercial organization to drive performance, ensure compliance, and deliver on business objectives. This role oversees sales and marketing operations including responsibilities across incentive compensation, field operations, CRM management, reporting, marketing operations, content management, speaker bureau execution, HCP contracting support, and materials management/fulfillment.

The ideal candidate will bring deep knowledge of the U.S. pharmaceutical marketplace, operational excellence, and compliance standards, along with proven experience enabling sales and marketing teams through scalable and efficient commercial operations.

Essential Functions:

Incentive Compensation & Field Operations
•    Design and oversee U.S. incentive compensation (IC) strategy, including plan design, modeling, governance, and ongoing operations.
•    Manage field operations support, including territory alignment, roster management, and call planning.
•    Partner with Sales leadership and Commercial Strategy team to monitor performance, execute field reporting, and provide actionable insights.

CRM & Commercial Technology Enablement
•    Lead U.S. CRM strategy and operations (e.g., Veeva CRM, Salesforce) to ensure usability, data integrity, and adoption by our commercial field teams.
•    Collaborate with IT and data strategy teams to implement and optimize commercial tools that support omnichannel engagement.

Commercial Reporting & Business Insights
•    Develop and oversee dashboards and reporting that provide timely, accurate visibility into U.S. sales and marketing performance.
•    Partner with Commercial Strategy team to ensure consistency in KPIs, performance measurement, and business reviews.

Marketing & Promotional Operations
•    Lead promotional content management systems, align teams to promotional review workflows, and materials fulfillment processes.
•    Oversee execution of speaker programs, including speaker bureau operations and logistics, ensuring compliance with U.S. regulatory standards.
•    Provide operational support for marketing campaigns and event execution.
•    Partner with Compliance and Legal to support U.S. HCP contracting and payment processes (Sunshine Act transparency reporting).

Governance, Compliance & Leadership
•    Ensure all commercial operations activities adhere to U.S. industry regulations (e.g., PhRMA Code, Sunshine Act, FDA promotional requirements).
•    Partner with Compliance, Legal, and Medical Affairs to proactively identify and mitigate operational risks.
•    Lead, coach, and develop a team of U.S. commercial operations professionals, fostering collaboration and excellence.

Experience and Education:

•    12–15 years of commercial operations experience in the U.S. pharmaceutical or biotech industry.
•    Proven leadership in incentive compensation, field operations, CRM management, reporting/analytics, and marketing operations.
•    Deep knowledge of U.S. commercial compliance requirements, including FDA promotional rules, PhRMA Code, and Sunshine Act.
•    Track record of collaborating effectively with Sales, Marketing, IT, Medical, Legal, Compliance, and Finance.
•    Bachelor’s degree in Business, Life Sciences, or related discipline required.
•    MBA or advanced degree preferred.

•    Strong strategic and operational leadership skills, with ability to translate business goals into execution.
•    Expertise in CRM platforms (Veeva, Salesforce) and reporting tools (Tableau, Power BI).
•    Excellent communication and stakeholder management skills across senior leadership and field teams.
•    Ability to lead in a fast-paced, dynamic environment with multiple priorities.
•    Demonstrated success in building and mentoring high-performing teams.

BENEFITS OF JOINING OUR TEAM 
•    Comprehensive medical benefits: we value access to healthcare for our patients as well as our employees •    Generous vacation / holiday time off: we care about our employees and encourage a balanced lifestyle 
•    Competitive 401(K) matching 
•    Bay Area office with great views, located in vibrant downtown San Mateo and within walking distance to restaurants, coffee shops, and the Cal Train 
•    A super cool team who’s excited to transform lives through innovative therapies 

$260,000 - $300,000 a year 

At Dompe, we offer an attractive compensation package to our team members. Any offer would include a competitive base salary (estimate shared above), incentive bonus, and benefits package customary to the position. Actual individual pay is determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. 

We believe that the unique contributions of all employees create our success. To ensure that our products and culture continue to incorporate everyone’s perspectives and experience, we never discriminate based on race, religion, national origin, gender identity or expression, sexual orientation, age, or marital, veteran, or disability status. All your information will be kept confidential according to EEO guidelines.